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For the Treatment of Rapid Eye Movement (REM) Sleep Behaviour Disorder (RBD) in Parkinson’s Disease and Lewy Body Dementia

Adults with learning disabilities

Sleep disturbance in adults with ADHD

Sleep disorders in the blind

Adults with complex neurodevelopmental disorders that the specialist considers eligible

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Nice TA:

Commissioning responsibility:


PbR excluded:


BNF chapter:
Central nervous system


Initiation of melatonin must be by a specialist in the indication being prescribed for and have clear review guidance.
Prescribing and review of melatonin in adults must follow the principles outlined in the Melatonin Pathway (adults) **Under development**.

Melatonin is suitable for prescribing for the treatment of REM RBD in PD and LBD when clonazepam is not considered to be appropriate.


LSCMMG Recommendation:

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Reason for decision:

Suitable for GP prescribing following recommendation/initiation by specialist

Decisions of Lancashire local decision making groups

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Last Updated: 04 - Jun - 2024