Medicine Recommendations

Erectile Dysfunction

Acute Ischaemic Stroke (NICE TA264)

NICE TA264 - Alteplase for treating acute ischaemic stroke (review of technology appraisal guidance 122) 

Thrombolysis in MI (NICE TA52)

NICE TA52 - Guidance on the use of drugs for early thrombolysis in the treatment of acute myocardial infarction

Massive pulmonary embolism (Thrombolysis)

 Influenza treatment & prophylaxis (NICE TA158 & 168)

NICE TA158 - Oseltamivir, amantadine (review) and zanamivir for the prophylaxis of influenza

NICE TA168 - Amantadine, oseltamivir and zanamivir for the treatment of influenza

Parkinson's disease (but not drug-induced extrapyramidal symptoms)

Arrhythmias

Schizophrenia

The colour classification was determined as part of the collaborative work between LCFT and medicines Management leads. Local pathways and patient safety were taken into consideration.

Neuropathic pain

Depressive illness

Migraine prophylaxis, Tension Type Headache prophylaxis

 Neuropathic pain (as per LSCMMG Guidelines)

Severe intractable insomnia only in patients already taking barbiturates

The colour classification was determined as part of the collaborative work between LCFT and medicines Management leads. Local pathways and patient safety were taken into consideration.

Essential thrombocythaemia in patients at risk of thrombo-haemorrhagic events who have not responded adequately to other drugs or who cannot tolerate other drugs.

Rheumatoid arthritis (CG79)

NICE CG79 - Rheumatoid arthritis: The management of rheumatoid arthritis in adults

Primary prevention of breast cancer in postmenopausal women at moderate or high risk

Hormonal treatment for early breast cancer (NICE TA112)

NICE TA112 - Hormonal therapies for the adjuvant treatment of early oestrogen-receptor-positive breast cancer 

Reversing anticoagulation from apixaban or rivaroxaban.

NICE TA 697 - Andexanet alfa for reversing anticoagulation from apixaban or rivaroxaban

All indications

Prevent of stroke and systemic embolism in people with nonvalvular atrial fibrillation (NICE TA275)

NICE TA275 - Apixaban for preventing stroke and systemic embolism in people with nonvalvular atrial fibrillation